The Modular Solution for Signal Analysis
A reliable description of the activity pattern of a single, well-isolated neuron is the key to many important experiments in neurophysiology. Once the quality of the recorded signal has been optimized and enhanced by the proper microelectrodes, amplification and bandpass filtering, the yield is determined by the power and flexibility of the spike discrimination and processing system. The BAK modular signal conditioners have been optimized for this purpose.

The figure at left
shows the proper interconnections for discrimination and visual on4ine
inspection of extracellular unit records. The DIS-1 multiplexed output
is viewed on one trace of an oscilloscope triggered by the threshold trigger
output of the DIS-1. Small bars in the drawing appear much as shown, indicating
the precise upper and lower bounds as well as the adjustable time of the
discrimination, set by the user to coincide with the portion of the wave-form
most distinctive from others exceeding the trigger level. To be certain
that only one unit has passed through the window and that others do not
exist with waveforms differing before the trigger, trigger an oscilloscope
trace (storage mode is particularly useful) from the acceptance pulse and
look at a delayed version of the input to the discriminator which has passed
through an Analog Delay (AD-3 and AD-6 dual delays now available). D1S-1's
can be easily chained for forward or backward multi-point discrimination.
Other forms of data reduction can greatly enhance on-line appreci9tlofl of the course of the experiment and reduce or even eliminate the need for complex computer data processing or taping The BAK 151-1 Interspike Interval Converter generates a dot or level display of the instantaneous frequency of firing (linear) of an accepted unit. The BAK DTC-1 Digital Timer Counter can accurately track both total events and latency from trigger events such as stimuli, with LED display and BCD outputs. The BAK RG1 Raster Stepper produces direct dot rastering and chart recorder rate profiles plus analog contour displays. The DO 1 Digital Delay can let you look back wards at spike events preceding behavioral criteria as shown.
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